Less risk of abuse potential, physical tolerance, and psychological dependence compared with true opioids
Dosing: average analgesic dosage: 50 mg tid;
maximum dosage: 400 mg/d
maximum dosage of 300 mg if >75 y/o
Associated with seizures in at-risk patients
When combined with other SNRIs & SSRIs, associated with seizures
Serotonin syndrome:
agitation or restlessness, diarrhea, tachycardia, BP elevation, typically occurring within several hours of taking the new medication or increasing the dose of the medication
Administer cautiously in patients at risk for respiratory depression even though Tramadol is not a true opioid.
