DRUG TREATMENT  -  Common Opioids -  
Fentanyl

Long-acting: Transdermal fentanyl (Duragesic patch)
  • Dosing: 12-25 µg/h patch q 72 h (avoid in opioid-naïve patients)
  • Peak effects occur 12-24 hours after application and effects last 12-24 hours after removal of patch 
  • Use product specific information for dose conversion from prior opioid
  • Use 50% of the dose in mild or moderate hepatic or renal impairment, avoid use in severe hepatic or renal impairment

Application & Handling
  • Apply to intact/non-irritated/non-irradiated skin on a flat surface.
  • Skin may be prepped by clipping hair, washing site with water only
  • Rotate site of application.
  • Do not cut.
  • Avoid exposure to heat.
  • Avoid accidental contact when holding or caring for children.
  • Dispose of used/unused patches by folding the adhesive side together and flushing down the toilet.

Specific contraindications:
  • Management of acute or intermittent pain, or in patients who require opioid analgesia for a short period of time.
  • Management of post-operative pain, including use after outpatient or day surgery.
  • Management of mild pain